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Article

Control of ColE2 plasmid replication: regulation of Rep expression by a plasmid-coded antisense RNA.

Molecular & general genetics : MGG - 8 Jul 1994

Takechi S, Yasueda H, Itoh T

Abstract excerpt

We isolated and characterized mutants of ColE2 with increased copy number (cop) and those with reduced sensitivity to the wild-type incA gene (inc). Both types of mutations were single-base substitutions in the incA region and simultaneously increased the plasmid copy number and reduced the inhibitory activity of the incA gene on ColE2 DNA replication. Most of the cop mutations also reduced sensitivity to the...

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Identifiers

PMID: 8041361
DOI: 10.1007/BF00280186

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Related research

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Research trail→

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Control of ColE2 plasmid replication: regulation of Rep expression by a plasmid-coded antisense RNA.PMID 8041361Read ↗

Control of ColE2 DNA replication: in vitro binding of the antisense RNA to the Rep mRNA.Semantic proximity Read ↗

Control of replication of plasmid R1: the intergenic region between copA and repA modulates the level of expression of repA.Semantic proximity Read ↗

The effects of RNA degradation enzymes on antisense RNAI controlling ColE2 plasmid copy number.Semantic proximity Read ↗

Control of replication of plasmid R1: the duplex between the antisense RNA, CopA, and its target, CopT, is processed specifically in vivo and in vitro by RNase III.Semantic proximity Read ↗

Regulation of replication of plasmid R1: an analysis of the intergenic region between copA and repA.Semantic proximity Read ↗

Replication initiator protein mRNA of ColE2 plasmid and its antisense regulator RNA are under the control of different degradation pathways.Semantic proximity Read ↗

Mutations in an antisense RNA, involved in the replication control of a repABC plasmid, that disrupt plasmid incompatibility and mediate plasmid speciation.Semantic proximity Read ↗

Importance of the leader region of mRNA for translation initiation of ColE2 Rep protein.Semantic proximity Read ↗

The plasmid ColIb-P9 antisense Inc RNA controls expression of the RepZ replication protein and its positive regulator repY with different mechanisms.Semantic proximity Read ↗

Modulation of ColE1-like plasmid replication for recombinant gene expression.Semantic proximity Read ↗

Regulation of plasmid R1 replication: PcnB and RNase E expedite the decay of the antisense RNA, CopA.Semantic proximity Read ↗

Positive and negative regulations of plasmid CoLIb-P9 repZ gene expression at the translational level.Semantic proximity Read ↗

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