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Article

Degradation pathway of CopA, the antisense RNA that controls replication of plasmid R1.

Microbiology (Reading, England) - 1 Jul 1998

Söderbom Fredrik, Wagner E Gerhart H

Abstract excerpt

RNA decay in bacteria is carried out by a number of enzymes that participate in the coordinated degradation of their substrates. Endo- and exonucleolytic cleavages as well as polyadenylation are generally involved in determining the half-life of RNAs. Small, untranslated antisense RNAs are suitable model systems to study decay. A study of the pathway of degradation of CopA, the copy number regulator RNA of...

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Identifiers

PMID: 9695924
DOI: 10.1099/00221287-144-7-1907

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Degradation pathway of CopA, the antisense RNA that controls replication of plasmid R1.PMID 9695924Read ↗

Absence of RNASE III alters the pathway by which RNAI, the antisense inhibitor of ColE1 replication, decays.Semantic proximity Read ↗

The effects of RNA degradation enzymes on antisense RNAI controlling ColE2 plasmid copy number.Semantic proximity Read ↗

Regulation of plasmid R1 replication: PcnB and RNase E expedite the decay of the antisense RNA, CopA.Semantic proximity Read ↗

Replication initiator protein mRNA of ColE2 plasmid and its antisense regulator RNA are under the control of different degradation pathways.Semantic proximity Read ↗

RNA degradation in Escherichia coli regulated by 3' adenylation and 5' phosphorylation.Semantic proximity Read ↗

The Escherichia coli pcnB gene promotes adenylylation of antisense RNAI of ColE1-type plasmids in vivo and degradation of RNAI decay intermediates.Semantic proximity Read ↗

Rapid degradation of polyadenylated oop RNA.Semantic proximity Read ↗

Control of replication of plasmid R1: the duplex between the antisense RNA, CopA, and its target, CopT, is processed specifically in vivo and in vitro by RNase III.Semantic proximity Read ↗

An unusually long-lived antisense RNA in plasmid copy number control: in vivo RNAs encoded by the streptococcal plasmid pIP501.Semantic proximity Read ↗

Initial events in the degradation of the polycistronic puf mRNA in Rhodobacter capsulatus and consequences for further processing steps.Semantic proximity Read ↗

Control of replication of plasmid R1: the intergenic region between copA and repA modulates the level of expression of repA.Semantic proximity Read ↗

Oligoribonuclease is an essential component of the mRNA decay pathway.Semantic proximity Read ↗

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