Article
Mutations and deletions within the S8-S9 interdomain region abolish complementation of N- and C-terminal domains of Ca(2+)-activated K+ (BK) channels.
Biochemical and biophysical research communications - 26 Nov 1997
Wood L S, Vogeli G
Abstract excerpt
A full length alpha-subunit of the Ca(2+)-activated K+ (BK) channel with an inactivating mutation in the C-terminus can complement a functional C-terminal fragment. We analyzed deletions and amino acid changes within the S8-S9 interdomain region for their ability to allow complementation. Cys612 and His616 that are located in a region that contains two overlapping signature sequences, a immunoglobulin signature...
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