Article
Epidermal growth factor regulates protein kinase A activity in murine fibrosarcoma cells: differences between metastatic and nonmetastatic tumor cell variants.
Cancer research - 1 Dec 1997
Fishman D, Galitzki L, Priel E, Segal S
Abstract excerpt
The interplay between cyclic AMP (cAMP)-dependent protein kinase A (PKA)- and p21ras-mediated signaling pathways is expected to determine further loss, maintenance, or modulation of differentiation and proliferation of a particular cell. Therefore, the relationship and nature of the cross-talk be...
Topics
- 3T3 Cells
- Animals
- Benzylidene Compounds
- Bucladesine
- Clone Cells
- Culture Media, Serum-Free
- Cyclic AMP
- Cyclic AMP-Dependent Protein Kinases
- Enzyme Induction
- Enzyme Inhibitors
- Epidermal Growth Factor
- ErbB Receptors
- Fibroblast Growth Factors
- Fibrosarcoma
- Genetic Variation
- Mice
- Mice, Inbred C3H
- Mice, Inbred C57BL