cAMP Signaling in Cancer: A PKA-CREB and EPAC-Centric Approach

doi:10.3390/cells11132020

Article

cAMP Signaling in Cancer: A PKA-CREB and EPAC-Centric Approach

24 Jun 2022

Abstract excerpt

Cancer is one of the most common causes of death globally. Despite extensive research and considerable advances in cancer therapy, the fundamentals of the disease remain unclear. Understanding the key signaling mechanisms that cause cancer cell malignancy may help to uncover new pharmaco-targets. Cyclic adenosine monophosphate (cAMP) regulates various biological functions, including those in malignant cells....

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