Article
Escherichia coli cells expressing a mutant glyV (glycine tRNA) gene have a UVM-constitutive phenotype: implications for mechanisms underlying the mutA or mutC mutator effect.
Journal of bacteriology - 1 Dec 1997
Murphy H S, Humayun M Z
Abstract excerpt
Transfection of M13 single-stranded viral DNA bearing a 3,N4-ethenocytosine lesion into Escherichia coli cells pretreated with UV results in a significant elevation of mutagenesis at the lesion site compared to that observed in untreated cells. This response, termed UVM, for UV modulation of muta...
Topics
- Anticodon
- Aspartic Acid
- Base Sequence
- Cytosine
- DNA Replication
- Escherichia coli
- Genes, Bacterial
- Glycine
- Methylnitronitrosoguanidine
- Molecular Sequence Data
- Mutagenesis
- Mutagens
- Mutation
- Phenotype
- RNA, Transfer, Gly
- Rec A Recombinases
- Ultraviolet Rays