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The Candida albicans CDR3 gene codes for an opaque-phase ABC transporter

1 Dec 1997

Abstract excerpt

We report the cloning and functional analysis of a third member of the CDR gene family in Candida albicans, named CDR3. This gene codes for an ABC (ATP-binding cassette) transporter of 1,501 amino acids highly homologous to Cdr1p and Cdr2p (56 and 55% amino acid sequence identity, respectively), two transporters involved in fluconazole resistance in C. albicans. The predicted structure of Cdr3p is typical of the...

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PMID: 9393682
DOI: 10.1128/jb.179.23.7210-7218.1997

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