Article
Mechanism of transdominant inhibition of CCR5-mediated HIV-1 infection by ccr5delta32.
The Journal of biological chemistry - 5 Dec 1997
Benkirane M, Jin D Y, Chun R F, Koup R A, Jeang K T
Abstract excerpt
Human chemokine receptor 5 (CCR5) functions as a co-receptor for Human immunodeficiency virus (HIV-1) infection. CCR5 is a seven-transmembrane cell surface receptor. Recently, a naturally occurring mutation of CCR5, ccr5Delta32, has been described. A small number of Caucasians are homozygously cc...
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