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Article

Role of the genetic variant CCR5Δ32 in HBV infection and HBV/HIV co-infection.

Virus research - 1 Feb 2020

Ellwanger Joel Henrique, Kulmann-Leal Bruna, Wolf Jonas Michel, Michita Rafael Tomoya, Simon Daniel, Lunge Vagner Ricardo, Chies José Artur Bogo

Abstract excerpt

CCR5 is a chemokine receptor that mediates the action of inflammatory cells, besides acting as an HIV co-receptor. CCR5Δ32 states for a genetic variant containing a 32 base pair deletion in the coding region of the CCR5 gene. In homozygosis, CCR5Δ32 results in the lack of CCR5 expression on the cell surface, which was associated with protection against HIV infection. Heterozygous individuals for CCR5Δ32 have a...

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Identifiers

PMID: 31837381
DOI: 10.1016/j.virusres.2019.197838

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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