Article
TGF-beta1 in colonic neoplasia: a genetic molecular and immunohistochemical study.
Journal of experimental & clinical cancer research : CR - 1 Sept 1997
Cardillo M R, Yap E
Abstract excerpt
Transforming growth factor-beta proteins are key regulators of cellular growth and differentiation. To understand the role of TGF-beta in colonic tumour progression, 47 paraffin embedded samples from colonic tumours (13 adenomas, and 34 adenocarcinomas) were studied. Gene mutations in the region...
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