Article
Transforming growth factor beta 1 (TGFB1) gene polymorphisms and risk of advanced colorectal adenoma.
Carcinogenesis - 1 Sept 2007
Berndt Sonja I, Huang Wen-Yi, Chatterjee Nilanjan, Yeager Meredith, Welch Robert, Chanock Stephen J, Weissfeld Joel L, Schoen Robert E, Hayes Richard B
Abstract excerpt
Transforming growth factor beta 1 (TGFB1) is a multifunctional cytokine that has been implicated in the pathogenesis of colorectal neoplasia. To investigate the association between genetic variants in TGFB1 and the risk of colorectal adenoma, we conducted a case-control study of 754 advanced adenoma cases and 769 controls from the baseline screening exam of the Prostate, Lung, Colorectal and Ovarian Cancer...
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