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Article

Transforming growth factor-[beta]1 -509T reduces risk of colorectal cancer, but not adenoma in Koreans.

Cancer science - 1 Mar 2007

Chung Su J, Kim Joo S, Jung Hyun C, Song In S

Abstract excerpt

The proliferation of colorectal epithelial cells is regulated by various stimuli including cytokines and growth factors, thus the variants of those genes can modify the colorectal cancer risk. TGF-[beta]1 can act as both a tumor suppressor and a stimulator of tumor progression. TGF-[beta]1 C-509T polymorphism in the promoter sequence has been associated with increased levels of plasma TGF-[beta]1 in individuals...

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Identifiers

PMID: 17214746
DOI: 10.1111/j.1349-7006.2007.00401.x
PMCID: PMC11159075

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Transforming growth factor-[beta]1 -509T reduces risk of colorectal cancer, but not adenoma in Koreans.PMID 17214746Read ↗

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Meta-analyses of the associations between four common TGF-β1 genetic polymorphisms and risk of colorectal tumor.Semantic proximity Read ↗

An updated meta-analysis on the association of TGF-β1 gene promoter -509C/T polymorphism with colorectal cancer risk.Semantic proximity Read ↗

TGFB1 509 C/T polymorphism and colorectal cancer risk: a meta-analysis.Semantic proximity Read ↗

Transforming growth factor beta-1 C-509T polymorphism and cancer risk: a meta-analysis of 55 case-control studies.Semantic proximity Read ↗

Genetic polymorphism in the transforming growth factor beta1 gene (-509 C/T and -800 G/A) and colorectal cancer.Semantic proximity Read ↗

Genetic polymorphisms of transforming growth factor-beta1 and its receptors and colorectal cancer susceptibility: a population-based case-control study in China.Semantic proximity Read ↗

Transforming growth factor beta 1 (TGFB1) gene polymorphisms and risk of advanced colorectal adenoma.Semantic proximity Read ↗

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