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Article

TGFbeta1 polymorphism (L10P) and risk of colorectal adenomatous and hyperplastic polyps.

International journal of epidemiology - 1 Oct 2004

Sparks Rachel, Bigler Jeannette, Sibert Justin G, Potter John D, Yasui Yutaka, Ulrich Cornelia M

Abstract excerpt

BACKGROUND: Transforming growth factor-beta1 (TGFbeta1) is a multifunctional signalling molecule with a wide array of roles. Animal experiments suggest that TGFbeta1 plays a biphasic role in carcinogenesis by protecting against the early formation of benign epithelial growths, but promoting malig...

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Source

Identifiers

PMID: 15020570
DOI: 10.1093/ije/dyh102

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15020570-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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