Article
Mutational analysis of Cdc19p, a Schizosaccharomyces pombe MCM protein.
Genetics - 1 Nov 1997
Forsburg S L, Sherman D A, Ottilie S, Yasuda J R, Hodson J A
Abstract excerpt
The cdc19+ gene encodes an essential member of the MCM family of replication proteins in Schizosaccharomyces pombe. We have examined the structure and function of the Cdc19p protein using molecular and genetic approaches. We find that overproduction of wild-type Cdc19p in wild-type cells has no effect, but cdc19-P1 mutant cells do not tolerate elevated levels of other MCM proteins or overexpression of mutant...
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