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Article

Schizosaccharomyces pombe cdc4+ gene encodes a novel EF-hand protein essential for cytokinesis.

The Journal of cell biology - 1 Aug 1995

McCollum D, Balasubramanian M K, Pelcher L E, Hemmingsen S M, Gould K L

Abstract excerpt

Schizosaccharomyces pombe cells divide by medial fission. One class of cell division mutants (cdc), the late septation mutants, defines four genes: cdc3, cdc4, cdc8, and cdc12 (Nurse, P., P. Thuriaux, and K. Nasmyth. 1976. Mol. & Gen. Genet. 146:167-178). We have cloned and characterized the cdc4 gene and show that the predicted gene product. Cdc4p, is a 141-amino acid polypeptide that is similar in sequence to...

Topics

Amino Acid Sequence
Base Sequence
Cell Compartmentation
Cell Cycle Proteins
Cell Division
Cloning, Molecular
Cytoskeletal Proteins
Escherichia coli
F-Box Proteins
Fluorescent Antibody Technique

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Fungal Proteins

Genes, Fungal

Molecular Sequence Data

Mutation

Phenotype

Precipitin Tests

Protein Binding

Recombinant Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 7622565
DOI: 10.1083/jcb.130.3.651
PMCID: PMC2120525

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7622565-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Schizosaccharomyces pombe cdc4+ gene encodes a novel EF-hand protein essential for cytokinesis.PMID 7622565Read ↗

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