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Article

The function of plakophilin 1 in desmosome assembly and actin filament organization.

The Journal of cell biology - 3 Apr 2000

Hatzfeld M, Haffner C, Schulze K, Vinzens U

Abstract excerpt

Plakophilin 1, a member of the armadillo multigene family, is a protein with dual localization in the nucleus and in desmosomes. To elucidate its role in desmosome assembly and regulation, we have analyzed its localization and binding partners in vivo. When overexpressed in HaCaT keratinocytes, plakophilin 1 localized to the nucleus and to desmosomes, and dramatically enhanced the recruitment of desmosomal...

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Identifiers

PMID: 10747098
DOI: 10.1083/jcb.149.1.209
PMCID: PMC2175088

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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