Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fluorescence energy transfer detection as a homogeneous DNA diagnostic method.

Proceedings of the National Academy of Sciences of the United States of America - 30 Sept 1997

Chen X, Zehnbauer B, Gnirke A, Kwok P Y

Abstract excerpt

A homogeneous DNA diagnostic assay based on template-directed primer extension detected by fluorescence resonance energy transfer, named template-directed dye-terminator incorporation (TDI) assay, has been developed for mutation detection and high throughput genome analysis. Here, we report the successful application of the TDI assay to detect mutations in the cystic fibrosis transmembrane conductance regulator...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drosophila Proteins
Share to Genotype
Share to Heterozygote

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to HLA Antigens

Share to Homozygote

Share to Membrane Proteins

Share to Mutation

Share to Proto-Oncogene Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 9380706
DOI: 10.1073/pnas.94.20.10756
PMCID: PMC23476

Genes

CFTR
RET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fluorescence energy transfer detection as a homogeneous DNA diagnostic method.PMID 9380706Read ↗

Template-directed dye-terminator incorporation (TDI) assay: a homogeneous DNA diagnostic method based on fluorescence resonance energy transfer.Semantic proximity Read ↗

A separation-free assay for the detection of mutations: combination of homogeneous time-resolved fluorescence and minisequencing.Semantic proximity Read ↗

Genotyping by induced Förster Resonance Energy Transfer(iFRET) mechanism and simultaneous mutation scanning.Semantic proximity Read ↗

Homogeneous genotyping assays for single nucleotide polymorphisms with fluorescence resonance energy transfer detection.Semantic proximity Read ↗

DNA analysis by fluorescence quenching detection.Semantic proximity Read ↗

Label/quencher-free detection of single-nucleotide changes in DNA using isothermal amplification and G-quadruplexes.Semantic proximity Read ↗

Energy transfer cassettes for facile labeling of sequencing and PCR primers.Semantic proximity Read ↗

Hybridization-induced dequenching of fluorescein-labeled oligonucleotides: a novel strategy for PCR detection and genotyping.Semantic proximity Read ↗

Simultaneous detection of the C282Y, H63D and S65C mutations in the hemochromatosis gene using quenched-FRET real-time PCR.Semantic proximity Read ↗

A single nucleotide polymorphism melt curve assay employing an intercalating dye probe fluorescence resonance energy transfer for forensic analysis.Semantic proximity Read ↗

Rapid and quantitative DNA analysis of genetic mutations for polycystic kidney disease (PKD) using magnetic/luminescent nanoparticles.Semantic proximity Read ↗

Combinatorial fluorescence energy transfer tags for multiplex biological assays.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.