Article
Rapid and quantitative DNA analysis of genetic mutations for polycystic kidney disease (PKD) using magnetic/luminescent nanoparticles.
Analytical and bioanalytical chemistry - 1 Apr 2008
Son Ahjeong, Dhirapong Amy, Dosev Dosi K, Kennedy Ian M, Weiss Robert H, Hristova Krassimira R
Abstract excerpt
Rapid and accurate detection of genetic mutations based on nanotechnology would provide substantial advances in detection of polycystic kidney disease (PKD), a disease whose current methods of detection are cumbersome due to the large size and duplication of the mutated gene. In this study, a nanotechnology-based DNA assay was developed for detection of SNPs (single nucleotide polymorphisms) in a feline autosomal...
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