Article
DNA analysis by fluorescence quenching detection.
Genome research - 1 May 2003
Xiao Ming, Kwok Pui-Yan
Abstract excerpt
The analysis of human genetic variations such as single nucleotide polymorphisms (SNPs) has great applications in genome-wide association studies of complex genetic traits. We have developed an SNP genotyping method based on the primer extension assay with fluorescence quenching as the detection. The template-directed dye-terminator incorporation with fluorescence quenching detection (FQ-TDI) assay is based on...
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