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Article

Tumor necrosis factor-alpha gene polymorphism in chronic bronchitis.

American journal of respiratory and critical care medicine - 1 Nov 1997

Huang S L, Su C H, Chang S C

Abstract excerpt

Airway inflammation is an important pathologic feature in chronic bronchitis, and we hypothesized that individuals with greater inflammatory responses may be more likely to acquire the disease. A polymorphism at -308 position of the tumor necrosis factor-alpha (TNF-alpha) gene has been described, with the rarer allele, TNF2, demonstrated to have higher inducibility in vitro. We investigated the distribution of...

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Identifiers

PMID: 9372657
DOI: 10.1164/ajrccm.156.5.9609138

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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