Article
Association of TNF-alpha with severe respiratory syncytial virus infection and bronchial asthma.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology - 1 Mar 2009
Puthothu Beena, Bierbaum Sibylle, Kopp Matthias V, Forster Johannes, Heinze Jessica, Weckmann Markus, Krueger Marcus, Heinzmann Andrea
Abstract excerpt
Tumor necrosis factor (TNF-)alpha is a proinflammatory cytokine that is important in the innate host defence and thus in the defence of infectious agents. However, in excess it provokes the development of chronic inflammatory diseases. The aim of this study was to test association of TNF with severe RSV bronchiolitis as example of an infectious disease and asthma as representative for a chronic inflammatory...
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