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Article

Detection of mutations in the gyrA and parC genes in quinolone-resistant clinical isolates of Enterobacter cloacae.

The Journal of antimicrobial chemotherapy - 1 Oct 1997

Deguchi T, Yasuda M, Nakano M, Ozeki S, Kanematsu E, Nishino Y, Ishihara S, Kawada Y

Abstract excerpt

We have determined partial sequences of the gyrA and parC genes of Enterobacter cloacae type strain including the regions analogous to the quinolone resistance-determining region of the Escherichia coli gyrA gene. The deduced 65- and 49-amino acid sequences of the determined regions of the E. cloacae gyrA and parC genes were identical to the corresponding regions of the E. coli GyrA and ParC proteins,...

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Identifiers

PMID: 9372424
DOI: 10.1093/jac/40.4.543

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Detection of mutations in the gyrA and parC genes in quinolone-resistant clinical isolates of Enterobacter cloacae.PMID 9372424Read ↗

Detection of mutations in parC in quinolone-resistant clinical isolates of Escherichia coli.Semantic proximity Read ↗

Mutations in the gyrA and parC genes in fluoroquinolone-resistant clinical isolates of Pseudomonas aeruginosa.Semantic proximity Read ↗

Alterations in the GyrA subunit of DNA gyrase and the ParC subunit of topoisomerase IV in quinolone-resistant clinical isolates of Klebsiella pneumoniae.Semantic proximity Read ↗

Mutations in gyrA and parC genes in nalidixic acid-resistant Escherichia coli strains from food products, humans and animals.Semantic proximity Read ↗

Mutations in the quinolone resistance-determining regions of gyrA and parC in Enterobacteriaceae isolates from BrazilSemantic proximity Read ↗

Alterations in the GyrA Subunit of DNA Gyrase and the ParC Subunit of DNA Topoisomerase IV Associated with Quinolone Resistance in Enterococcus faecalisSemantic proximity Read ↗

Observation of a New Pattern of Mutations in gyrA and parC within Escherichia coli Exhibiting Fluroquinolone ResistanceSemantic proximity Read ↗

Alteration in the GyrA subunit of DNA gyrase and the ParC subunit of DNA topoisomerase IV in quinolone-resistant clinical isolates of Staphylococcus epidermidis.Semantic proximity Read ↗

Association of alterations in ParC and GyrA proteins with resistance of clinical isolates of Enterococcus faecium to nine different fluoroquinolones.Semantic proximity Read ↗

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Quinolone-resistant mutants of escherichia coli DNA topoisomerase IV parC gene.Semantic proximity Read ↗

Type II topoisomerase mutations in ciprofloxacin-resistant strains of Pseudomonas aeruginosa.Semantic proximity Read ↗

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