Article
Detection of mutations in the gyrA and parC genes in quinolone-resistant clinical isolates of Enterobacter cloacae.
The Journal of antimicrobial chemotherapy - 1 Oct 1997
Deguchi T, Yasuda M, Nakano M, Ozeki S, Kanematsu E, Nishino Y, Ishihara S, Kawada Y
Abstract excerpt
We have determined partial sequences of the gyrA and parC genes of Enterobacter cloacae type strain including the regions analogous to the quinolone resistance-determining region of the Escherichia coli gyrA gene. The deduced 65- and 49-amino acid sequences of the determined regions of the E. clo...
Topics
- Amino Acid Sequence
- Anti-Infective Agents
- Base Sequence
- DNA Gyrase
- DNA Topoisomerase IV
- DNA Topoisomerases, Type II
- Enterobacter cloacae
- Fluoroquinolones
- Genes, Bacterial
- Humans
- Microbial Sensitivity Tests
- Molecular Sequence Data
- Mutation