Article
Type II topoisomerase mutations in ciprofloxacin-resistant strains of Pseudomonas aeruginosa.
Antimicrobial agents and chemotherapy - 1 Jan 1999
Mouneimné H, Robert J, Jarlier V, Cambau E
Abstract excerpt
We determined the sequences of the quinolone resistance-determining regions of gyrA, gyrB, and parC genes for 30 clinical strains of Pseudomonas aeruginosa resistant to ciprofloxacin that were previously complemented by wild-type gyrA and gyrB plasmid-borne alleles and studied for their coresista...
Topics
- Amino Acid Sequence
- Anti-Infective Agents
- Base Sequence
- Ciprofloxacin
- DNA Gyrase
- DNA Topoisomerase IV
- DNA Topoisomerases, Type II
- Drug Resistance, Microbial
- Microbial Sensitivity Tests
- Molecular Sequence Data
- Mutation
- Pseudomonas aeruginosa
- Reverse Transcriptase Polymerase Chain Reaction