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Article

Birthdate and cell marker analysis of scrambler: a novel mutation affecting cortical development with a reeler-like phenotype.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Dec 1997

González J L, Russo C J, Goldowitz D, Sweet H O, Davisson M T, Walsh C A

Abstract excerpt

The reeler mutation in mice produces an especially well characterized disorder, with systematically abnormal migration of cerebral cortical neurons. The reeler gene encodes a large protein, termed Reelin, that in the cortex is synthesized and secreted exclusively in the Cajal-Retzius neurons of the cortical marginal zone (D'Arcangelo et al., 1995). In reeler mutant mice, loss of Reelin protein is associated with...

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PMID: 9364067
PMCID: PMC6573592

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Birthdate and cell marker analysis of scrambler: a novel mutation affecting cortical development with a reeler-like phenotype.PMID 9364067Read ↗

Cell-type-specific consequences of Reelin deficiency in the mouse neocortex, hippocampus, and amygdala.Semantic proximity Read ↗

Cerebellar disorganization characteristic of reeler in scrambler mutant mice despite presence of reelin.Semantic proximity Read ↗

Scrambler and yotari disrupt the disabled gene and produce a reeler-like phenotype in mice.Semantic proximity Read ↗

Expression of reelin, the gene responsible for the reeler mutation, in embryonic development and adulthood in the mouse.Semantic proximity Read ↗

The reeler gene-associated antigen on Cajal-Retzius neurons is a crucial molecule for laminar organization of cortical neurons.Semantic proximity Read ↗

Caudally pronounced deficiencies in preplate splitting and migration underly a rostro-caudal progression of cortical lamination defects in the reeler brain.Semantic proximity Read ↗

Novel genetic tools facilitate the study of cortical neuron migration.Semantic proximity Read ↗

A protein related to extracellular matrix proteins deleted in the mouse mutant reeler.Semantic proximity Read ↗

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Detection of the reelin breakpoint in reeler mice.Semantic proximity Read ↗

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