Article
Cell-type-specific consequences of Reelin deficiency in the mouse neocortex, hippocampus, and amygdala.
The Journal of comparative neurology - 1 Aug 2011
Boyle Maureen P, Bernard Amy, Thompson Carol L, Ng Lydia, Boe Andrew, Mortrud Marty, Hawrylycz Michael J, Jones Allan R, Hevner Robert F, Lein Ed S
Abstract excerpt
The disrupted cortical lamination phenotype in reeler mice and subsequent identification of the Reelin signaling pathway have strongly informed models of cortical development. We describe here a marker-based phenotyping approach to reexamine the cytoarchitectural consequences of Reelin deficiency, using high-throughput histology and newly identified panels of highly specific molecular markers. The resulting...
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