Article
Detection of the reelin breakpoint in reeler mice.
Brain research. Molecular brain research - 1 Jul 1996
D'Arcangelo G, Miao G G, Curran T
Abstract excerpt
Disruption of the reelin gene by partial deletion causes the neurological phenotype known as reeler. Here we report the cloning and sequencing of the reelin breakpoint region from the Jackson reeler strain (rl). Based on this sequence, we developed a polymerase chain reaction screen that allows t...
Topics
- Animals
- Base Sequence
- DNA, Complementary
- Mice
- Mice, Inbred Strains
- Mice, Neurologic Mutants
- Molecular Sequence Data
- Mutation
- Reelin Protein