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Article

HLA-DP polymorphism in Sudanese controls and patients with insulin-dependent diabetes mellitus.

Tissue antigens - 1 Aug 1992

Magzoub M M, Stephens H A, Sachs J A, Biro P A, Cutbush S, Wu Z, Bottazzo G F

Abstract excerpt

Human leukocyte antigen (HLA) genes are candidates for susceptibility to insulin-dependent diabetes mellitus (IDDM). The association of IDDM with particular DR and DQ alleles has been reported in all populations studied, but its association with HLA-DP alleles has been controversial. To address this question we analyzed 19 DPB1 and 2 DPA1 alleles and their associations in well-characterized Sudanese (an admixture...

Topics

Alleles
Autoradiography
Base Sequence
DNA
Diabetes Mellitus, Type 1
Genotype
HLA-DP Antigens
Humans
Molecular Sequence Data
Polymerase Chain Reaction
Polymorphism, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Prevalence

Sudan

Source

Identifiers

PMID: 1412418
DOI: 10.1111/j.1399-0039.1992.tb01961.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1412418-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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