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Article

Effect of early blockade of bradykinin B2-receptors on the blood pressure phenotype of normotensive and spontaneously hypertensive rats.

Pharmacological research - 1 Jun 1997

Emanueli C, Madeddu P

Abstract excerpt

We evaluated if chronic blockade of bradykinin B2-receptors by the long-acting antagonist Icatibant (D-Arg,[Hyp3,Thi5,D-Tic7,Oic8]-bradykinin) affects blood pressure of rats. Pairs of normotensive Wistar Kyoto rats or spontaneously hypertensive rats were mated and their offspring received Icatibant (25 nmol day-1 per kg body wt., s.c.) or vehicle from the 2nd day until the 7th week of life. Then, the...

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PMID: 9361315

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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