Article
Long-term effect on blood pressure of early brief treatment by different antihypertensive agents: a study in the prague hypertensive rat.
Kidney & blood pressure research - 1 Jan 1998
Heller J, Hellerová S
Abstract excerpt
In the Prague hypertensive rat (PHR), a strain of genetic hypertension derived from Wistar, administration of various antihypertensive drugs (AHD) during the developmental phase of hypertension (weeks 5-9 of life) prevents the rise of blood pressure. However, only drugs blocking the renin-angiotensin system (RAS, i.e. AT1-antagonist losartan and ACE inhibitor perindopril) have a long-term effect on blood pressure...
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