Article
Linkage analysis of manic depression (bipolar affective disorder) in Icelandic and British kindreds using markers on the short arm of chromosome 18.
Human heredity - 1 Jan 2000
Kalsi G, Smyth C, Brynjolfsson J, Sherrington R S, O'Neill J, Curtis D, Rifkin L, Murphy P, Petursson H, Gurling H M
Abstract excerpt
Attempts were made to follow up results of a previous linkage study which suggested that a locus-modifying susceptibility to bipolar and related unipolar affective disorder might be present in the pericentromeric region of the short arm of chromosome 18. Twenty-three multiply affected pedigrees collected from Iceland and the UK were genotyped using three highly polymorphic microsatellite markers at D18S37, D18S40...
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