Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Chromosome 18 DNA markers and manic-depressive illness: evidence for a susceptibility gene.

Proceedings of the National Academy of Sciences of the United States of America - 21 Jun 1994

Berrettini W H, Ferraro T N, Goldin L R, Weeks D E, Detera-Wadleigh S, Nurnberger J I, Gershon E S

Abstract excerpt

In the course of a systematic genomic survey, 22 manic-depressive (bipolar) families were examined for linkage to 11 chromosome 18 pericentromeric marker loci, under dominant and recessive models. Overall logarithm of odds score analysis for the pedigree series was not significant under either mo...

Topics

Bipolar Disorder
Centromere
Chromosomes, Human, Pair 18
DNA
GTP-Binding Proteins
Genetic Linkage
Genetic Markers
Genetic Predisposition to Disease
Humans
Lod Score
Pedigree

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Probability

Receptors, Corticotropin

Source

Open in PubMed Open full text

Identifiers

PMID: 8016089
DOI: 10.1073/pnas.91.13.5918
PMCID: PMC44108

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8016089-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Chromosome 18 DNA markers and manic-depressive illness: evidence for a susceptibility gene.PMID 8016089Read ↗

A chromosome 18 genetic linkage study in three large Belgian pedigrees with bipolar disorder.Semantic proximity Read ↗

Linkage analysis of manic depression (bipolar affective disorder) in Icelandic and British kindreds using markers on the short arm of chromosome 18.Semantic proximity Read ↗

Lack of evidence for a major locus for bipolar disorder in the pericentromeric region of chromosome 18 in Irish pedigrees.Semantic proximity Read ↗

Linkage of bipolar affective disorder to chromosome 18 markers in a new pedigree series.Semantic proximity Read ↗

Linkage studies of bipolar disorder with chromosome 18 markers.Semantic proximity Read ↗

Evaluation of parent-of-origin effect in bipolar affective disorder relating to susceptibility loci on chromosome 18.Semantic proximity Read ↗

Linkage analysis between pericentrometric markers on chromosome 18 and bipolar disorder: a replication test.Semantic proximity Read ↗

Genetic linkage mapping for a susceptibility locus to bipolar illness: chromosomes 2, 3, 4, 7, 9, 10p, 11p, 22, and Xpter.Semantic proximity Read ↗

A linkage study of bipolar illness.Semantic proximity Read ↗

Genetic analysis of bipolar disorder: summary of GAW10.Semantic proximity Read ↗

Evidence for linkage of bipolar disorder to chromosome 18 with a parent-of-origin effect.Semantic proximity Read ↗

Genetic analysis of psychiatric disorders associated with human chromosome 18.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.