Article
Linkage studies of bipolar disorder in the region of the Darier's disease gene on chromosome 12q23-24.1.
American journal of medical genetics - 24 Apr 1995
Dawson E, Parfitt E, Roberts Q, Daniels J, Lim L, Sham P, Nöthen M, Propping P, Lanczik M, Maier W
Abstract excerpt
We have recently described a family in which there is cosegregation of major affective disorder with Darier's disease and have mapped this autosomal dominant skin disorder to 12q23-q24.1. This has provided an interesting candidate region for genetic studies of bipolar disorder. We have studied the segregation of seven markers spanning the Darier's disease locus in 45 bipolar disorder pedigrees and found modest...
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