Article
Linkage studies of bipolar disorder with chromosome 18 markers.
American journal of medical genetics - 15 Oct 1999
Bowen T, Kirov G, Gill M, Spurlock G, Vallada H P, Murray R M, McGuffin P, Collier D A, Owen M J, Craddock N
Abstract excerpt
Evidence consistent with the existence of genetic linkage between bipolar disorder and three regions on chromosome 18, the pericentromeric region, 18q21, and 18q22-q23 have been reported. Some analyses indicated greater evidence for linkage in pedigrees in which paternal transmission of disease occurs. We have undertaken linkage analyses using 12 highly polymorphic markers spanning these three regions of interest...
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