Article
Linkage analyses of chromosome 18 markers do not identify a major susceptibility locus for bipolar affective disorder in the Old Order Amish.
American journal of human genetics - 1 Sept 1995
Pauls D L, Ott J, Paul S M, Allen C R, Fann C S, Carulli J P, Falls K M, Bouthillier C A, Gravius T C, Keith T P
Abstract excerpt
Previously reported linkage of bipolar affective disorder to DNA markers in the pericentromeric region of chromosome 18 was reexamined in a larger homogeneous sample of Old Order Amish families. Four markers (D18S21, D18S53, D18S44, and D18S40) were examined in three kindreds containing 31 bipola...
Topics
- Bipolar Disorder
- Chromosome Mapping
- Chromosomes, Human, Pair 18
- Ethnicity
- Female
- Genetic Linkage
- Genetic Markers
- Genotype
- Humans
- Lod Score
- Male