Article
Simultaneous detection of FV Q506 and prothrombin 20210 A variation by allele-specific PCR.
Haematologica - 1 Mar 1999
Mitterer M, Lanthaler A J, Mair W, Giacomuzzi K, Coser P
Abstract excerpt
BACKGROUND AND OBJECTIVE: Factor V Leiden is the most important risk factor for hereditary thromboembolism, whereas the mutation in the 3'-untranslated region of the prothrombin gene seems to be only a mild risk factor for thrombotic events. On the other hand the factor V mutation (Arg 506) is frequently coinherited with the prothrombin 3'-untranslated region G20210A variant and there is increasing evidence that...
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