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Article

p53/E1b58kDa complex regulates adenovirus replication.

Virology - 27 Oct 1997

Ridgway P J, Hall A R, Myers C J, Braithwaite A W

Abstract excerpt

We have explored a role for the adenovirus (Ad5) E1b58kDa/p53 protein complex in adenovirus replication. This was done by using virus mutants containing different defects in the E1b58kDa gene and cell lines that express either a wild-type p53 protein or a mutant p53 protein. We find that infection of wild-type p53-containing cells with wild-type Ad5 causes a shutoff of p53 and alpha-actin protein synthesis by...

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Identifiers

PMID: 9356351
DOI: 10.1006/viro.1997.8782

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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