p53/E1b58kDa complex regulates adenovirus replication.

doi:10.1006/viro.1997.8782

Back to search

Article

p53/E1b58kDa complex regulates adenovirus replication.

Virology - 27 Oct 1997

Ridgway P J, Hall A R, Myers C J, Braithwaite A W

Abstract excerpt

We have explored a role for the adenovirus (Ad5) E1b58kDa/p53 protein complex in adenovirus replication. This was done by using virus mutants containing different defects in the E1b58kDa gene and cell lines that express either a wild-type p53 protein or a mutant p53 protein. We find that infectio...

Topics

Adenoviridae
Adenovirus E1B Proteins
Cell Line
Humans
Mutation
Tumor Suppressor Protein p53
Virus Replication

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.