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Article

Adenovirus E4orf4 protein downregulates MYC expression through interaction with the PP2A-B55 subunit.

Journal of virology - 1 Oct 2008

Ben-Israel Haggit, Sharf Rakefet, Rechavi Gideon, Kleinberger Tamar

Abstract excerpt

The adenovirus E4 open reading frame 4 (E4orf4) protein is a multifunctional viral regulator that is involved in the temporal regulation of viral gene expression by modulating cellular and viral genes at the transcription and translation levels and by controlling alternative splicing of adenoviral late mRNAs. When expressed individually, E4orf4 induces apoptosis in transformed cells. Using oligonucleotide...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18653458
DOI: 10.1128/JVI.00791-08
PMCID: PMC2546959

Genes

MYC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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