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Article

p21/waf1/cip1 and mdm-2 expression in breast carcinoma patients as related to prognosis.

International journal of cancer - 21 Oct 1997

Jiang M, Shao Z M, Wu J, Lu J S, Yu L M, Yuan J D, Han Q X, Shen Z Z, Fontana J A

Abstract excerpt

p21/waf1/cip1 and mdm-2 are downstream effectors of p53. p21 plays a major role in negatively regulating cell-cycle progression, while mdm-2 inhibits p53 effects, and its role has been implicated in oncogenesis. In this study, we investigated the expression profiles of p21, mdm-2 and p53 in human breast-carcinoma tissues. The aim was to determine whether a correlation exists between the expression profiles of...

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Identifiers

PMID: 9355976
DOI: 10.1002/(sici)1097-0215(19971021)74:5<529::aid-ijc9>3.0.co;2-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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