Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interaction between bcl-2 and p21 (WAF1/CIP1) in breast carcinomas with wild-type p53

26 Sept 1997

Abstract excerpt

The bcl-2 protein is found to be over-expressed in many types of human tumours and is a potent inhibitor of apoptosis. The exact mechanism by which bcl-2 prevents apoptosis and exercises its oncogenic effect is still unclear. Other studies on cell lines have reported that bcl-2 over-expression is related to suppression of p21 (WAF1/CIP). We have investigated the relationship between bcl-2 protein over-expression...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Lipids, and Metabolism
Share to Cancer-related Molecular Pathways
Share to Cell death mechanisms and regulation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9334807
DOI: 10.1002/(sici)1097-0215(19970926)73:1<38::aid-ijc7>3.0.co;2-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interaction between bcl-2 and p21 (WAF1/CIP1) in breast carcinomas with wild-type p53PMID 9334807Read ↗

BCL-2 family proteins: Regulators of cell death involved in the pathogenesis of cancer and resistance to therapySemantic proximity Read ↗

BCL-2 family proteins: regulators of cell death involved in the pathogenesis of cancer and resistance to therapy.Semantic proximity Read ↗

The role of the Bcl-2 protein family in cancer.Semantic proximity Read ↗

p21/waf1/cip1 and mdm-2 expression in breast carcinoma patients as related to prognosis.Semantic proximity Read ↗

Regulators of apoptosis in human breast cancer.Semantic proximity Read ↗

bcl-2 protein expression is associated with a prognostically favourable phenotype in breast cancer irrespective of p53 immunostaining.Semantic proximity Read ↗

Relationship between abnormal p53 protein and failure to express p21 protein in human breast carcinomas.Semantic proximity Read ↗

Role of Three Cancer ≪Master Genes≫ P53, Bcl2 and C-Myc on the Apoptotic ProcessSemantic proximity Read ↗

c-myc, p53 andbcl-2, apoptosis-related genes in infiltrating breast carcinomas: Evidence of a link between bcl-2 protein over-expression and a lower risk of metastasis and death in operable patientsSemantic proximity Read ↗

The p53 positive Bcl-2 negative phenotype is an independent marker of prognosis in breast cancer.Semantic proximity Read ↗

Down-regulation of bcl-2 by p53 in breast cancer cells.Semantic proximity Read ↗

The p53/p21 Complex Regulates Cancer Cell Invasion and Apoptosis by Targeting Bcl-2 Family ProteinsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.