Article
Relationship between p53 gene abnormalities and other tumour characteristics in breast-cancer prognosis.
International journal of cancer - 22 Apr 1996
Seshadri R, Leong A S, McCaul K, Firgaira F A, Setlur V, Horsfall D J
Abstract excerpt
The prognostic significance of p53 gene abnormalities was investigated in 919 primary breast-cancer patients. p53 expression and tumour-cell proliferation fraction determined by MIB-1 count, p53 exon 5 and 6 mutations and HER-2/neu oncogene amplification were detected by immunohistochemistry, PCR...
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