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Article

The p53 positive Bcl-2 negative phenotype is an independent marker of prognosis in breast cancer.

International journal of cancer - 15 Mar 2007

Rolland Phil, Spendlove Ian, Madjd Zahra, Madjid Zahra, Rakha Emad A, Patel Poulam, Ellis Ian O, Durrant Lindy

Abstract excerpt

The purpose of this work was to determine if the immunohistochemical p53 (+) Bcl-2 (-) phenotype predicts survival in breast cancer patients. Tissue from 819 cases of resected primary breast cancer, presented between 1986 and 1998, were assembled in tissue microarray format. Clinicopathological data and prospective disease specific survival data were collected prospectively and immunohistochemical analyses of p53...

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Identifiers

PMID: 17187363
DOI: 10.1002/ijc.22430

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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