Article
SecY and SecA interact to allow SecA insertion and protein translocation across the Escherichia coli plasma membrane.
The EMBO journal - 3 Nov 1997
Matsumoto G, Yoshihisa T, Ito K
Abstract excerpt
SecA, the preprotein-driving ATPase in Escherichia coli, was shown previously to insert deeply into the plasma membrane in the presence of ATP and a preprotein; this movement of SecA was proposed to be mechanistically coupled with preprotein translocation. We now address the role played by SecY,...
Topics
- Adenosine Triphosphatases
- Alleles
- Bacterial Proteins
- Biological Transport, Active
- Escherichia coli
- Escherichia coli Proteins
- Macromolecular Substances
- Membrane Proteins
- Membrane Transport Proteins
- Mutagenesis
- Phenotype
- Point Mutation
- Protein Precursors
- SEC Translocation Channels
- SecA Proteins
- Suppression, Genetic
- Transduction, Genetic