Article
Genetic dissection of SecA: suppressor mutations against the secY205 translocase defect.
Genes to cells : devoted to molecular & cellular mechanisms - 1 Dec 2000
Matsumoto G, Nakatogawa H, Mori H, Ito K
Abstract excerpt
BACKGROUND: The driving force for protein translocation across the bacterial plasma membrane is provided by SecA ATPase, which undergoes striking conformational changes characterized by the membrane insertion and deinsertion cycle. This action of SecA requires the membrane-embedded SecYEG complex. Previously, we have identified a cold-sensitive secY mutation (secY205), affecting the most carboxy-terminal...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.