Article
Translocation of proteins through the Sec61 and SecYEG channels.
Current opinion in cell biology - 1 Aug 2009
Mandon Elisabet C, Trueman Steven F, Gilmore Reid
Abstract excerpt
The Sec61 and SecYEG translocation channels mediate the selective transport of proteins across the endoplasmic reticulum and bacterial inner membrane, respectively. These channels are also responsible for the integration of membrane proteins. To accomplish these two critical events in protein expression, the transport channels undergo conformational changes to permit the export of lumenal domains and the...
Topics
- Cell Membrane
- Endoplasmic Reticulum
- Escherichia coli
- Escherichia coli Proteins
- Lipid Bilayers
- Membrane Proteins
- Methanococcus
- Models, Biological
- Molecular Conformation
- Mutation
- Protein Conformation