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Article

Multiple SecA molecules drive protein translocation across a single translocon with SecG inversion.

The Journal of biological chemistry - 2 Jan 2012

Morita Kazuhiro, Tokuda Hajime, Nishiyama Ken-Ichi

Abstract excerpt

SecA is a translocation ATPase that drives protein translocation. D209N SecA, a dominant-negative mutant, binds ATP but is unable to hydrolyze it. This mutant was inactive to proOmpA translocation. However, it generated a translocation intermediate of 18 kDa. Further addition of wild-type SecA caused its translocation into either mature OmpA or another intermediate of 28 kDa that can be translocated into mature...

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Identifiers

PMID: 22074917
DOI: 10.1074/jbc.M111.301754
PMCID: PMC3249098

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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