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The use of glutamine synthetase as a selection marker: recent advances in Chinese hamster ovary cell line generation processes

2013-12-01

Abstract excerpt

Central to the needs of the biopharmaceutical industry to support the development of innovative biologics and biosimilars are more effective and efficient manufacturing processes which require highly productive cell lines with desired quality attributes. New designs of molecules such as antibody humanization have greatly reduced immunogenicity concerns, and advances in cell culture technology including media optim...

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Literature Corpus work
712200a8-a3f9-51ff-b60b-7c7853af5de5
DOI
10.4155/pbp.13.56
Open publication

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The use of glutamine synthetase as a selection marker: recent advances in Chinese hamster ovary cell line generation processesDOI 10.4155/pbp.13.56
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