Article
Arginine transport in human monocytic leukemia THP-1 cells during macrophage differentiation
17 May 2011
Abstract excerpt
L-arginine metabolism in myeloid cells plays a central role in the processes of macrophage activation and in the regulation of immune responses. In this study, we investigated arginine transport activity and the expression of the related transporter genes during the differentiation of monocytes to macrophages. We show here that the induction of THP-1 monocyte differentiation by PMA markedly increases the...