Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Generation of infectious virus particles by transient co-expression of human immunodeficiency virus type 1 gag mutants.

The Journal of general virology - 1 Oct 1997

Chen Y L, Ts'ai P W, Yang C C, Wang C T

Abstract excerpt

We have demonstrated that COS7 cells transiently co-expressing myristylation-defective (Myr-) and protease-defective (PR-) human immunodeficiency virus (HIV) mutants can release infectious virions when co-transfected with an amphotropic murine leukaemia virus envelope protein expression plasmid (...

Topics

Animals
COS Cells
Gene Products, gag
Genes, gag
Genetic Complementation Test
HIV Protease
HIV-1
Leukemia Virus, Murine
Mutation
Myristic Acids
Protein Precursors
Protein Processing, Post-Translational

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Transfection

Virion

Source

Identifiers

PMID: 9349470
DOI: 10.1099/0022-1317-78-10-2497

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9349470-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Generation of infectious virus particles by transient co-expression of human immunodeficiency virus type 1 gag mutants.PMID 9349470Read ↗

Overexpression of the gag-pol precursor from human immunodeficiency virus type 1 proviral genomes results in efficient proteolytic processing in the absence of virion productionSemantic proximity Read ↗

Assembly, processing, and infectivity of human immunodeficiency virus type 1 gag mutantsSemantic proximity Read ↗

The C-Terminal Half of the Human Immunodeficiency Virus Type 1 Gag Precursor Is Sufficient for Efficient Particle AssemblySemantic proximity Read ↗

Assembly-defective point mutants of the human immunodeficiency virus type 1 Gag precursor phenotypically expressed in recombinant baculovirus-infected cells.Semantic proximity Read ↗

Myristoylation-dependent replication and assembly of human immunodeficiency virus 1.Semantic proximity Read ↗

trans-acting proteins involved in RNA encapsidation and viral assembly in human immunodeficiency virus type 1.Semantic proximity Read ↗

Characterization of deletion mutations in the capsid region of human immunodeficiency virus type 1 that affect particle formation and Gag-Pol precursor incorporationSemantic proximity Read ↗

Myristoylation of gag proteins of HIV-1 plays an important role in virus assembly.Semantic proximity Read ↗

Characterization of human immunodeficiency virus type-1 (HIV-1) particles that express protease-reverse transcriptase fusion proteins.Semantic proximity Read ↗

Nucleocapsid‐independent assembly of coronavirus‐like particles by co‐expression of viral envelope protein genes.Semantic proximity Read ↗

The nonmyristylated Pr160gag-pol polyprotein of human immunodeficiency virus type 1 interacts with Pr55gag and is incorporated into viruslike particlesSemantic proximity Read ↗

Murine leukemia virus nucleocapsid mutant particles lacking viral RNA encapsidate ribosomes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.