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Article

Assembly, processing, and infectivity of human immunodeficiency virus type 1 gag mutants

1 Jul 1993

Abstract excerpt

We studied the effects of gag mutations on human immunodeficiency virus type 1 (HIV-1) assembly, processing, and infectivity by using a replication-defective HIV expression system. HIV mutants were screened for infectivity by transduction of a selectable marker and were examined for assembly by monitoring particle release from transfected cells. Gag protein processing and reverse transcriptase activities of...

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Identifiers

PMID: 7685414
DOI: 10.1128/jvi.67.7.4264-4273.1993

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