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Article

Myristoylation-dependent replication and assembly of human immunodeficiency virus 1.

Proceedings of the National Academy of Sciences of the United States of America - 1 Jan 1990

Bryant M, Ratner L

Abstract excerpt

Covalent linkage of myristic acid to the N-terminal glycine residue of Pr55gag, the precursor of the major structural proteins of human immunodeficiency virus 1 (HIV-1), facilitates an essential step in virus assembly and propagation. Substitution of the myristoyl-acceptor glycine with alanine, i...

Topics

Alanine
Base Sequence
Cell Fractionation
Cell Line
Gene Products, gag
Glycine
HIV-1
HeLa Cells
Humans
Kinetics
Molecular Sequence Data
Mutation
Myristic Acid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Myristic Acids

Oligonucleotide Probes

Protein Processing, Post-Translational

Subcellular Fractions

Transfection

Source

Open in PubMed Open full text

Identifiers

PMID: 2405382
DOI: 10.1073/pnas.87.2.523
PMCID: PMC53297

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2405382-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Myristoylation-dependent replication and assembly of human immunodeficiency virus 1.PMID 2405382Read ↗

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